About Conolidine alkaloid for chronic pain
Most not too long ago, it's been identified that conolidine and the above derivatives act over the atypical chemokine receptor 3 (ACKR3. Expressed in similar parts as classical opioid receptors, it binds to a big selection of endogenous opioids. Not like most opioid receptors, this receptor functions as being a scavenger and won't activate a next m